PAM polyclonal antibody
产品名称： PAM polyclonal antibody
英文名称： PAM polyclonal antibody
产品编号： PAB7587
产品价格： null
产品产地： 台湾
品牌商标： Abnova
更新时间： null
使用范围：
亚诺法生技股份有限公司（Abnova)
- 联系人 :
- 地址 : 台湾台北市内湖区洲子街 108 号 9 楼
- 邮编 : 11493
- 所在区域 : 台湾
- 电话 : +886-920**1152 点击查看
- 传真 : 点击查看
- 邮箱 : sales@abnova.com.tw
- Specification
- Product Description:
- Goat polyclonal antibody raised against synthetic peptide of PAM.
- Immunogen:
- A synthetic peptide corresponding to human PAM.
- Sequence:
- C-DQEKEDDGSESEE
- Host:
- Goat
- Theoretical MW (kDa):
- 108, 101, 96.3, 98.8
- Reactivity:
- Human
- Specificity:
- This antibody is expected to recognize all reported isoforms (NP_000910.2; NP_620121.1; NP_620176.1 and NP_620177.1).
- Form:
- Liquid
- Purification:
- Antigen affinity purification
- Concentration:
- 0.5 mg/mL
- Storage Buffer:
- In Tris saline, pH 7.3 (0.5% BSA, 0.02% sodium azide)
- Storage Instruction:
- Store at -20°C.
Aliquot to avoid repeated freezing and thawing.
- Quality Control Testing:
- Antibody Reactive Against Synthetic Peptide.
- Recommend Usage:
- ELISA (1:4000)
Western Blot (0.3-1 ug/mL)
The optimal working dilution should be determined by the end user.
- Note:
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Publication Reference
- 1.
- Human peptidylglycine alpha-amidating monooxygenase: cDNA, cloning and functional expression of a truncated form in COS cells.
Glauder J, Ragg H, Rauch J, Engels JW.Biochem Biophys Res Commun. 1990 Jun 15;169(2):551-8.
- Entrez GeneID:
- 5066
- Protein Accession#:
- NP_000910.2;NP_620121.1;NP_620176.1;NP_620177.1
- Gene Name:
- PAM
- Gene Alias:
- PAL,PHM
- Gene Description:
- peptidylglycine alpha-amidating monooxygenase
- Omim ID:
- 170270
- Gene Ontology:
- Hyperlink
- Gene Summary:
- This gene encodes a multifunctional protein. It has two enzymatically active domains with catalytic activities - peptidylglycine alpha-hydroxylating monooxygenase (PHM) and peptidyl-alpha-hydroxyglycine alpha-amidating lyase (PAL). These catalytic domains work sequentially to catalyze neuroendocrine peptides to active alpha-amidated products. Multiple alternatively spliced transcript variants encoding different isoforms have been described for this gene but some of their full length sequences are not yet known. [provided by RefSeq
- Other Designations:
- pancreatic peptidylglycine alpha-amidating monooxygenase,peptidyl alpha-amidating enzyme,peptidyl-alpha-hydroxyglycine alpha-amidating lyase,peptidylglycine 2-hydroxylase,peptidylglycine alpha-hydroxylating monooxygenase
- Related Disease